effect of soy phytoestrogen on metabolic and hormonal disturbance of women with polycystic ovary syndrome

نویسندگان

behnaz khani assistant professor, department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

ferdous mehrabian associate professor, obstetrics and gynecology department, school of medicine, isfahan university of medical science, isfahan, iran

elaheh khalesi department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

azadeh eshraghi school of pharmacy, isfahan university of medical sciences, isfahan, iran

چکیده

background: phytoestrogens are a group of plants derived compounds with weekly estrogen effect that appear to have protective effects on metabolic and hormonal abnormalities of women with polycystic ovary syndrome (pcos). so the aim of this study was to investigate the effect of soy phytoestrogens on reproductive hormones and lipid profiles in pcos women. methods: in this quasi-randomized trial, 146 subjects with pcos were divided into two groups; the experimental group who received genistein (bergamon, italy) 18 mg twice a day orally and the control group that received similar capsules with cellulose for 3 months. hormonal features and lipid profiles were measured before and after 3 months of supplement therapy. results: after 3 months of supplement therapy there were no statistically significant differences in high density lipoprotein cholesterol (hdl) and follicle stimulating hormone (fsh) serum levels in genistein and placebo group before and after treatment; however serum levels of luteinizing hormone (lh), triglyceride (tg), low density lipoprotein cholesterol (ldl), dehydroepiandrostrone sulfate (dheas) and testosterone were significantly decreased after 3 months therapy in genistein group. conclusions: genistein consumption may prevent cardiovascular and metabolic disorders in pcos patients by improving their reproductive hormonal and lipid profiles. keywords: polycystic ovary syndrome, genistein, phytoestrogens , cardiovascular diseases.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of soy phytoestrogen on metabolic and hormonal disturbance of women with polycystic ovary syndrome

BACKGROUND Phytoestrogens are a group of plants derived compounds with weekly estrogen effect that appear to have protective effects on metabolic and hormonal abnormalities of women with polycystic ovary syndrome (PCOS). So the aim of this study was to investigate the effect of soy phytoestrogens on reproductive hormones and lipid profiles in PCOS women. METHODS In this quasi-randomized trial...

متن کامل

Effect of aerobic training in women with polycystic ovary syndrome

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age and is associated with various metabolic perturbations. Chronic low grade inflammation has been reported to participate in the pathogenesis of metabolic syndrome. In this study we examined the effects of 8 weeks aerobic training on serum C-reactive protein level and cardiometab...

متن کامل

I-30: Prevalence of Metabolic Syndrome in Women with Polycystic Ovary Syndrome

Background: Metabolic syndrome is a disorder which is composed of several metabolic abnormalities: glucose intolerance, dyslipidemia, obesity and hypertension. PCOS which is characterized by menstrual irregularities and hyperandrogenism, is a common endocrinological disorder in female reproductive age. The prevalence of the syndrome is 5-10%. Insulin resistance is a common feature of the PCOS (...

متن کامل

Metabolic and Endocrine Characteristics of Indian Women with Polycystic Ovary Syndrome

Objective Polycystic ovary syndrome (PCOS) is one of the most common endocrinological disorders among women of reproductive age and the leading cause of female infertility. This study intends to evaluate the lipid profile, hormonal levels [free T3 (fT3), free T4 (fT4), thyroid stimulating hormone (TSH), insulin, luteinizing hormone (LH), follicle stimulating hormone (FSH), and prolactin] in PCO...

متن کامل

The comparison of dietary intake of macronutrients in polycystic ovary syndrome with and without metabolic syndrome

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women. The prevalence of PCOS among Iranian women is 14.6% based on the Rotterdam definition. PCOS can increase the risk of chronic metabolic complications. Metabolic syndrome (MetS) is one of the most important of them. Insulin resistance is fundamental in PCOS and MetS pathophysiology. MetS ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of research in medical sciences

جلد ۱۶، شماره ۳، صفحات ۰-۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023